[CAS NO. 2070018-30-1] IDO-IN-3
PRODUCTS SPECIFICATIONS [2070018-30-1]
DESCRIPTION [2070018-30-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 359.15 |
| Molecular Formula | C11H12BrFN6O2 |
| SMILES | O/N=C(NC1=CC(Br)=C(F)C=C1)\C2=NON=C2NCCN |
Summary
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase ( IDO ) inhibitor with an IC 50 of 290 nM.
IC50 & Target
|
IDO 290 nM (IC 50 ) |
IDO 98 nM (IC 50 , in HeLa cell) |
In Vitro
IDO-IN-3 (Compound 4c) is a potent (HeLa IC 50 =98 nM) inhibitor of IDO [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 27.5 mg/mL ( 76.57 mM ; Need ultrasonic and warming)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.7844 mL | 13.9218 mL | 27.8435 mL |
| 5 mM | 0.5569 mL | 2.7844 mL | 5.5687 mL |
| 10 mM | 0.2784 mL | 1.3922 mL | 2.7844 mL |