[CAS NO. 2088956-21-0]  Anticancer agent 7

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PRODUCTS SPECIFICATIONS [2088956-21-0]

Catalog
HY-W072940
Brand
MCE
CAS
2088956-21-0

DESCRIPTION [2088956-21-0]

Overview

MDL-
Molecular Weight575.38
Molecular FormulaC24H19Cl2F3N2O5S
SMILESO[C@@H]1[C@@](COC[C@H]1NS(=O)(C2=CC=C(C=C2)OC(F)(F)F)=O)([H])N3C4=CC=C(Cl)C=C4C5=CC(Cl)=CC=C53

For research use only. We do not sell to patients.

Summary

Anticancer agent 7 (Example 5) is an anti-cancer agent with an IC 50 of 5 μM for H1650 lung cancer cells [1] .


In Vitro

Anticancer agent 7 exhibits anti-proliferative effects. Anticancer agent 7 is useful in the treatment of a variety of disorders, including as a therapy in cancer treatment [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay [1]

Cell Line: H1650 lung cancer cells
Concentration:
Incubation Time: 48 hours
Result: IC 50 value of 5 μM.

Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 173.80 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7380 mL 8.6899 mL 17.3798 mL
5 mM 0.3476 mL 1.7380 mL 3.4760 mL
10 mM 0.1738 mL 0.8690 mL 1.7380 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.34 mM); Clear solution

* All of the co-solvents are available by MCE.