MDL | - |
---|---|
Molecular Weight | 373.35 |
Molecular Formula | C19H17F2N3O3 |
SMILES | O=C(C1=C(C)C(C(C(NCC#C)=O)=O)=C(C)N1C)NC2=CC=C(F)C(F)=C2 |
GLP-26 (0.7-1.7 μM; 3 days) reduces secreted HBeAg in HepNTCP-DL cells transfected with HBV
wild type, with EC
50
values of 0.7 μM
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay [2]
Cell Line: | HepNTCP-DL cells |
Concentration: | 0.7-1.7 μM |
Incubation Time: | 3 days |
Result: | Reduced secreted HBeAg in HepNTCP-DL cells. |
Solid
Room temperature in continental US; may vary elsewhere.
Powder | -20°C | 3 years |
---|---|---|
4°C | 2 years | |
In solvent | -80°C | 6 months |
-20°C | 1 month |
DMSO : 125 mg/mL ( 334.81 mM ; Need ultrasonic)
Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
---|
1 mM | 2.6785 mL | 13.3923 mL | 26.7845 mL |
5 mM | 0.5357 mL | 2.6785 mL | 5.3569 mL |
10 mM | 0.2678 mL | 1.3392 mL | 2.6785 mL |
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.08 mg/mL (5.57 mM); Clear solution