[CAS NO. 2135309-51-0] IDH1 Inhibitor 7-d 2
PRODUCTS SPECIFICATIONS [2135309-51-0]
DESCRIPTION [2135309-51-0]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 461.48 |
| Molecular Formula | C22H22D2F3N7O |
| SMILES | O=C1NC([2H])([2H])[C@H](C(C)C)N1C2=NC(N[C@H](C3=CN(C4=CC=C(C(F)(F)F)C=C4)C=N3)C)=NC=C2 |
Summary
IDH1 Inhibitor 7-d 2 is the deuterium labeled IDH1 Inhibitor 7 (HY-150238). IDH1 Inhibitor 7 is an IDH1 inhibitor with an IC 50 of less than 100 nM [1] [2] .
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
References