MDL | - |
---|---|
Molecular Weight | 568.59 |
Molecular Formula | C29H31F3N6O3 |
SMILES | O=C(N1CCC(CN2C(C3=NN(C)C(C4=CC=C(CN)C=C4)=C3N=C2)=O)(O)CC1)C[C@@H](C(F)(F)F)C5=CC=CC=C5 |
USP7-IN-3 (Compound 5) is a potent and selective allosteric ubiquitin-specific protease 7 ( USP7 ) inhibitor [1] .
USP7 [1]
Solid
Room temperature in continental US; may vary elsewhere.
Powder | -20°C | 3 years |
---|---|---|
In solvent | -80°C | 6 months |
-20°C | 1 month |
DMSO : 90 mg/mL ( 158.29 mM ; Need ultrasonic)
Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
---|
1 mM | 1.7587 mL | 8.7937 mL | 17.5874 mL |
5 mM | 0.3517 mL | 1.7587 mL | 3.5175 mL |
10 mM | 0.1759 mL | 0.8794 mL | 1.7587 mL |
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 4.5 mg/mL (7.91 mM); Clear solution