[CAS NO. 2245892-85-5] NVP-BHG712isomer

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PRODUCTS SPECIFICATIONS [2245892-85-5]

Catalog

HY-13258

Brand

MCE

CAS

2245892-85-5

MDL	-
Molecular Weight	503.48
Molecular Formula	C26H20F3N7O
SMILES	CC1=CC=C(C=C1NC2=NC(C3=CC=CN=C3)=NC4=NN(C)C=C42)C(NC5=CC=CC(C(F)(F)F)=C5)=O

For research use only. We do not sell to patients.

NVP-BHG712 isomer, a regioisomer of NVP-BHG712, shows conserved non-bonded binding to EPHA2 and EPHB4 ^[1] .

IC50: 163 nM (EPHA2) ^[1] .

NVP-BHG712 isomer exhibits IC ₅₀ values of 163 nM and 1660 nM for EPHA2 and EPHA4, respectively ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 50 mg/mL ( 99.31 mM ; Need ultrasonic)

Preparing
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Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (4.97 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (4.97 mM); Clear solution

* All of the co-solvents are available by MCE.