[CAS NO. 2271358-65-5] UAMC-3203hydrochloride
PRODUCTS SPECIFICATIONS [2271358-65-5]
DESCRIPTION [2271358-65-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 508.12 |
| Molecular Formula | C25H38ClN5O2S |
| SMILES | O=S(C(C=C1NCC2=CC=CC=C2)=CC=C1NC3CCCCC3)(NCCN4CCNCC4)=O.Cl |
2 Publications Citing Use of MCE
Summary
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC 50 of 12 nM [1] .
IC50 & Target
IC50: 12 nM (Ferroptosis) [1]
In Vivo
No toxicity is observed in mice after repeated injections of UAMC-3203 (20 µmol/kg; injected intraperitoneally; daily, over a period of 4 weeks) [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
| Animal Model: | Wild type mice derived from a Gpx4 fl/fl breeding [1] |
| Dosage: | 20 µmol/kg |
| Administration: | Injected intraperitoneally; daily, over a period of 4 weeks |
| Result: | No toxicity was observed. |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 50 mg/mL ( 98.40 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.9680 mL | 9.8402 mL | 19.6804 mL |
| 5 mM | 0.3936 mL | 1.9680 mL | 3.9361 mL |
| 10 mM | 0.1968 mL | 0.9840 mL | 1.9680 mL |