[CAS NO. 2278274-34-1]  FT206

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [2278274-34-1]

Catalog
HY-138698
Brand
MCE
CAS
2278274-34-1

DESCRIPTION [2278274-34-1]

Overview

MDL-
Molecular Weight447.60
Molecular FormulaC25H29N5OS
SMILESO=C(C1=C(C2=CC=C(C)N=C2S1)N)N[C@@H]3CC4=CC=C(N5CC6NC(CC6)C5)C=C4CC3

For research use only. We do not sell to patients.

Summary

FT206 is an inhibitor of carboxamides as ubiquitin-specific protrase extracted from patent WO 2020033707 A1, example 11-1 [1] .


IC50 & Target

Carboxamides as ubiquitin-specific protrase


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 150 mg/mL ( 335.12 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2341 mL 11.1707 mL 22.3414 mL
5 mM 0.4468 mL 2.2341 mL 4.4683 mL
10 mM 0.2234 mL 1.1171 mL 2.2341 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 5 mg/mL (11.17 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 5 mg/mL (11.17 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 3.75 mg/mL (8.38 mM); Clear solution

* All of the co-solvents are available by MCE.