[CAS NO. 2408810-59-1] Alismanol M

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PRODUCTS SPECIFICATIONS [2408810-59-1]

Catalog

HY-N10640

Brand

MCE

CAS

2408810-59-1

DESCRIPTION [2408810-59-1]

Overview

MDL	-
Molecular Weight	504.70
Molecular Formula	C30H48O6
SMILES	C[C@@]12[C@@]3(C([C@](O)(CC3)[C@H](C)C[C@H](O)[C@@H](O)C(C)(O)C)=CC([C@@]1([H])[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC2)C)=O)C

For research use only. We do not sell to patients.

Summary

Alismanol M is a farnesoid X receptor ( FXR ) agonist with an EC ₅₀ value of 50.25 μM. Alismanol M is a protostane-type triterpenoid that can be isolated from the rhizome of Alisma orientale . Alismanol M can be used for the research of cholestasis and nonalcoholic steatohepatitis ^[1] .

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References

[1] Luan ZL, et al. Highly potent non-steroidal FXR agonists protostane-type triterpenoids: Structure-activity relationship and mechanism. Eur J Med Chem. 2019 Nov 15;182:111652.