[CAS NO. 2448475-19-0] (R)-VX-984

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PRODUCTS SPECIFICATIONS [2448475-19-0]

Catalog

HY-19939S2

Brand

MCE

CAS

2448475-19-0

MDL	-
Molecular Weight	415.49
Molecular Formula	C23H21D2N7O
SMILES	O=C(C1=CC=NC2=C([C@@H](C)CNC3=CC(C4=C([2H])N=C(C)N=C4[2H])=NC=N3)C=CC=C12)NC

For research use only. We do not sell to patients.

(R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent DNA-PK inhibitor .

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 11.36 mg/mL ( 27.34 mM ; Need ultrasonic)

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Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 1.14 mg/mL (2.74 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1.14 mg/mL (2.74 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 1.14 mg/mL (2.74 mM); Clear solution

* All of the co-solvents are available by MCE.