[CAS NO. 2505001-54-5] SR15006

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PRODUCTS SPECIFICATIONS [2505001-54-5]

Catalog

HY-139691

Brand

MCE

CAS

2505001-54-5

MDL	-
Molecular Weight	385.87
Molecular Formula	C16H20ClN3O4S
SMILES	O=C(NCC(N1CCN(S(=O)(C)=O)CC1)=O)/C=C/C2=CC=CC(Cl)=C2

For research use only. We do not sell to patients.

SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) with an IC ₅₀ of 41.6 nM in DLD-1/pGL4.18hKLF5p cells) ^[1] .

SR15006 (1 μM or 10 μM; DLD-1 CRC cells) causes a significant reduction in the levels of tested cyclins over the course of 72 hours ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Solid

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

In Vitro:

DMSO : 100 mg/mL ( 259.15 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (6.48 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (6.48 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (6.48 mM); Clear solution

* All of the co-solvents are available by MCE.