[CAS NO. 2650944-83-3] FATP1-IN-2
PRODUCTS SPECIFICATIONS [2650944-83-3]
DESCRIPTION [2650944-83-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 353.39 |
| Molecular Formula | C19H20FN5O |
| SMILES | O=C(CN1CCN(CC1)C2=NC=C(C=C2)F)C3=C(C)N=C4C=CC=CN43 |
1 Publications Citing Use of MCE
Summary
FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 ( FATP1 ) inhibitor (human IC 50 =0.43 μM, mouse IC 50 =0.39 μM) [1] .
In Vivo
FATP1-IN-2 (10 mg/kg; p.o.) shows a C
max
value above the mouse IC
50
value
[1]
.
FATP1-IN-2 (3, 10, 30 mg/kg; p.o.; 4 weeks) shows TG content of each tissue does not change at any dose
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
| Animal Model: | Mice [1] |
| Dosage: | 10 mg/kg |
| Administration: | P.o. |
| Result: | Showed a C max value above the mouse IC 50 value. |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 282.97 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.8297 mL | 14.1487 mL | 28.2973 mL |
| 5 mM | 0.5659 mL | 2.8297 mL | 5.6595 mL |
| 10 mM | 0.2830 mL | 1.4149 mL | 2.8297 mL |