[CAS NO. 2691846-93-0] Sortilin antagonist 1

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PRODUCTS SPECIFICATIONS [2691846-93-0]

Catalog

HY-148650

Brand

MCE

CAS

2691846-93-0

DESCRIPTION [2691846-93-0]

Overview

MDL	-
Molecular Weight	356.42
Molecular Formula	C20H24N2O4
SMILES	CC(C)(C)CC[C@@H](C(O)=O)NC(C(C=N1)=CC=C1OC2=CC=CC=C2)=O

For research use only. We do not sell to patients.

Summary

Sortilin antagonist 1 (compound 44) is a sortilin antagonist with an IC ₅₀ value of 20 nM for inhibiting Neurotensin (NTS) binds to sortilin. Neurotensin is a sortilin ligand. Sortilin antagonist 1 can be used for the research of neurological disease ^[1] .

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Kjoelby, Mads Fuglsang, et al. A sortilin antagonist for use in the prevention or treatment of hearing loss. WO2022074119. 2022.