[CAS NO. 2756014-25-0] IGUANA-1

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PRODUCTS SPECIFICATIONS [2756014-25-0]

Catalog

HY-148466

Brand

MCE

CAS

2756014-25-0

DESCRIPTION [2756014-25-0]

Overview

MDL	-
Molecular Weight	491.97
Molecular Formula	C27H26ClN3O4
SMILES	O=CO.COC1=CC(Cl)=CC=C1C(N2C3=NCCC2)=CN3C(C=C4)=CC=C4C5=CC=CC=C5OC

For research use only. We do not sell to patients.

Summary

IGUANA-1 is a potent inhibitor of ALDH1B1 , which is a mitochondrial enzyme that promotes colorectal and pancreatic cancer . IGUANA-1 has significant inhibition against cancer cells ^[1] .

IC50 & Target

ALDH1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Feng Z, et al. Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1. Nat Chem Biol. 2022 Oct;18(10):1065-1075.