[CAS NO. 2785430-86-4]  ALK5-IN-30

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PRODUCTS SPECIFICATIONS [2785430-86-4]

Catalog
HY-151279
Brand
MCE
CAS
2785430-86-4

DESCRIPTION [2785430-86-4]

Overview

MDL-
Molecular Weight444.51
Molecular FormulaC24H25FN8
SMILESCN1CCN(C2=CC=C(NC3=NC=CC(NC4=C5C=C(F)C=C(C)C5=NN=C4)=N3)C=C2)CC1

For research use only. We do not sell to patients.

Summary

ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC 50 s <10 nM [1] .


IC50 & Target

IC50: <10 nM (ALK5) [1]


In Vitro

ALK5-IN-30 (EX-07) exhibits kinase selectivity on ALK5 over ALK2, with selectivity index of ALK2/ALK5 >10 [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Please store the product under the recommended conditions in the Certificate of Analysis.