[CAS NO. 302-22-7] Chlormadinone acetate

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PRODUCTS SPECIFICATIONS [302-22-7]

Catalog

HY-B1095

Brand

MCE

CAS

302-22-7

DESCRIPTION [302-22-7]

Overview

MDL	MFCD00056471
Molecular Weight	404.93
Molecular Formula	C23H29ClO4
SMILES	CC([C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])C=C(Cl)C4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O

For research use only. We do not sell to patients.

Summary

Chlormadinone acetate is a steroidal progestin, with antiandrogen and antiestrogenic effects.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT01123538	University Hospital of North Norway	Pharmacogenomics\|Systems Biology	December 2008	Phase 4
NCT01608698	Mahidol University	Body Weight Changes	June 2012	Phase 4

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL ( 24.70 mM ; Need ultrasonic)

H ₂ O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4696 mL	12.3478 mL	24.6956 mL
5 mM	0.4939 mL	2.4696 mL	4.9391 mL
10 mM	0.2470 mL	1.2348 mL	2.4696 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 1 mg/mL (2.47 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1 mg/mL (2.47 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 1 mg/mL (2.47 mM); Clear solution

* All of the co-solvents are available by MCE.

Synonyms

Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-chloro-

Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-, acetate

17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione

RS 1280

17-Acetoxy-6-chloro-6-dehydroprogesterone

CAP

Chlormadinone acetate

6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione

6-Chloro-Δ⁶-17-acetoxyprogesterone

6-Chloro-Δ⁶-dehydro-17-acetoxyprogesterone

6-Chloro-6-dehydro-17-acetoxyprogesterone

6-Chloro-6-dehydro-17α-acetoxyprogesterone

6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione acetate

6-Chloro-17α-hydroxy-Δ⁶-progesterone acetate

6-Chloro-Δ^4,6-pregnadien-17α-ol-3,20-dione 17-acetate

6-Chloro-pregna-4,6-dien-17α-ol-3,20-dione acetate

6-Dehydro-6-chloro-17α-acetoxyprogesterone

Lormin

Lutinyl

Skedule TM

Matrol

6-Chloro-17-hydroxypregna-4,6-diene-3,20-dione acetate

Ay 13390-6

6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate

Gestafortin

6-Chloro-17α-acetoxy-4,6-pregnadiene-3,20-dione

6-Chloro-6,7-dehydro-17-acetoxyprogesterone

6-Chloro-Δ⁶-[17α]acetoxyprogesterone

Chlormadinon acetate

17-Acetoxy-6-chloropregna-4,6-diene-3,20-dione

17α-Acetoxy-6-chloro-6,7-dehydroprogesterone

Luteran

Lutoral (Syntex)

Normenon

Menstridyl

Cero

Verton

17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione

Synchrosyn P

Bovisynchron

Traslan

Clordion

Retex

Synchrosyn

Prostal

NSC 92338

Natrol

Lutoral

Fertiletten

Chronosyn

Cyclonorm

Bellissima