[CAS NO. 302-84-1] DL-Serine
PRODUCTS SPECIFICATIONS [302-84-1]
DESCRIPTION [302-84-1]
Overview
| MDL | MFCD00064223 |
|---|---|
| Molecular Weight | 105.09 |
| Molecular Formula | C3H7NO3 |
| SMILES | NC(CO)C(O)=O |
Summary
DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) [1] .
In Vivo
Subcutaneous injection of DL-serine increases the number and size of renal tubular cell tumors in male W rats treated with 500 or 1,000 ppm N-ethyl-N-hydroxyethylnitrosamine
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
H 2 O : 33.33 mg/mL ( 317.16 mM ; Need ultrasonic)
DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 9.5157 mL | 47.5783 mL | 95.1565 mL |
| 5 mM | 1.9031 mL | 9.5157 mL | 19.0313 mL |
| 10 mM | 0.9516 mL | 4.7578 mL | 9.5157 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 25 mg/mL (237.89 mM); Clear solution; Need ultrasonic
References
- [1] Hiasa Y, et al. DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. J Natl Cancer Inst. 1984 Jul;73(1):297-9.
- [2] VARMA, J. P., et al. Effect of Alanine, Serine and Glutamic Acid on the Multiplication of Tobacco Mosaic Virus in Tobacco. Journal of Phytopathology. 1967, 58(1), 53-58.
Synonyms