[CAS NO. 31008-19-2] Fargesin

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PRODUCTS SPECIFICATIONS [31008-19-2]

Catalog

HY-N0719

Brand

MCE

CAS

31008-19-2

DESCRIPTION [31008-19-2]

Overview

MDL	MFCD07781423
Molecular Weight	370.40
Molecular Formula	C21H22O6
SMILES	COC1=CC=C([C@H]2OC[C@@]3([H])[C@H](C4=CC=C(OCO5)C5=C4)OC[C@]32[H])C=C1OC

For research use only. We do not sell to patients.

Summary

Fargesin is a bioactive neolignan isolated from magnolia plants , with antihypertensive and anti-inflammatory effects ^[1] ^[2] ^[3] .

In Vitro

Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-ĸB ^[3] .
Fargesin as a potential β₁ adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis ^[4] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 337.47 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6998 mL	13.4989 mL	26.9978 mL
5 mM	0.5400 mL	2.6998 mL	5.3996 mL
10 mM	0.2700 mL	1.3499 mL	2.6998 mL

* Please refer to the solubility information to select the appropriate solvent.

References

Synonyms

1,3-Benzodioxole, 5-[(1R,3aS,4S,6aS)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-, rel-

1,3-Benzodioxole, 5-[4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-, (1α,3aα,4β,6aα)-(±)-

1H,3H-Furo[3,4-c]furan, 1α-(3,4-dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-4β-[(3,4-methylenedioxy)phenyl]-

1H,3H-Furo[3,4-c]furan, 1,3-benzodioxole deriv.

rel-5-[(1R,3aS,4S,6aS)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole

Fargesin

1,3-Benzodioxole, 5-[4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-, (1α,3aα,4β,6aα)-

(±)-Fargesin