[CAS NO. 3160-91-6]  Moroxydinehydrochloride

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PRODUCTS SPECIFICATIONS [3160-91-6]

Catalog
HY-B0420A
Brand
MCE
CAS
3160-91-6

DESCRIPTION [3160-91-6]

Overview

MDLMFCD00012798
Molecular Weight207.66
Molecular FormulaC6H14ClN5O
SMILESN=C(N1CCOCC1)NC(N)=N.Cl

For research use only. We do not sell to patients.

Summary

Moroxydine hydrochloride (ABOB hydrochloride) is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines. Target: Influenza Virus Moroxydine hydrochloride (ABOB hydrochloride) is an antiviral drug that was originally developed in the 1950s as an influenza treatment. It has potential applications against a number of RNA and DNA viruses [1]. Structurally moroxydine is a heterocyclic biguanidine. Moroxydine was reported in March 2014 that three kindergartens in two provinces of China had been found to be secretly dosing their students with moroxydine hydrochloride to try to prevent them from becoming ill. The kindergartens are paid only for the days that pupils attend and wanted to ensure that they maximised their earnings [2].


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)


Solvent & Solubility

In Vitro:

H 2 O : ≥ 100 mg/mL ( 481.56 mM )

DMSO : 50 mg/mL ( 240.78 mM ; Need ultrasonic)

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8156 mL 24.0778 mL 48.1556 mL
5 mM 0.9631 mL 4.8156 mL 9.6311 mL
10 mM 0.4816 mL 2.4078 mL 4.8156 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 100 mg/mL (481.56 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (12.04 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (12.04 mM); Clear solution

  • 4.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (12.04 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

4-Morpholinecarboximidamide, N-(aminoiminomethyl)-, hydrochloride (1:1)
4-Morpholinecarboxamidine, N-amidino-, monohydrochloride
4-Morpholinecarboximidamide, N-(aminoiminomethyl)-, monohydrochloride
Guanidine, 4-morpholinecarboximidoyl-, hydrochloride
ABOB hydrochloride
Spenitol
Flumidin
Virustat
N1,N1-Anhydrobis(β-hydroxyethyl)biguanide hydrochloride
4-(Amidinoamidino)morpholine hydrochloride
Morpholinobiguanide monohydrochloride
Morpholinobiguanide hydrochloride
Virusmin
Moroxydine hydrochloride
Malinguchlorate
Miejunging