[CAS NO. 31721-94-5] 5,7-Dihydroxychromone
PRODUCTS SPECIFICATIONS [31721-94-5]
DESCRIPTION [31721-94-5]
Overview
| MDL | MFCD14583153 |
|---|---|
| Molecular Weight | 178.14 |
| Molecular Formula | C9H6O4 |
| SMILES | O=C1C=COC2=CC(O)=CC(O)=C12 |
1 Publications Citing Use of MCE
Summary
5,7-Dihydroxychromone, the extract of Cudrania tricuspidata , activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis . 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells [1] .
IC50 & Target
|
Nrf2 |
Caspase-3 |
Caspase-9 |
PARP |
Appearance
Solid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL ( 561.36 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 5.6136 mL | 28.0678 mL | 56.1356 mL |
| 5 mM | 1.1227 mL | 5.6136 mL | 11.2271 mL |
| 10 mM | 0.5614 mL | 2.8068 mL | 5.6136 mL |
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1.
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2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (14.03 mM); Clear solution
Synonyms