[CAS NO. 319-78-8] D-Isoleucine

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PRODUCTS SPECIFICATIONS [319-78-8]

Catalog

HY-I1070

Brand

MCE

CAS

319-78-8

DESCRIPTION [319-78-8]

Overview

MDL	MFCD00064221
Molecular Weight	131.17
Molecular Formula	C6H13NO2
SMILES	CC[C@@H](C)[C@@H](N)C(O)=O

For research use only. We do not sell to patients.

Summary

D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : < 1 mg/mL (insoluble or slightly soluble)

References

[1] Rosenberg D, et, al. Neuronal D-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity. J Neurosci. 2013 Feb 20;33(8):3533-44.

Synonyms

D-Isoleucine

Isoleucine, D-

(R)-Isoleucine

(2R,3R)-2-Amino-3-methylpentanoic acid