[CAS NO. 330628-04-1]  DMT-dG(dmf)Phosphoramidite

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PRODUCTS SPECIFICATIONS [330628-04-1]

Catalog
HY-138585
Brand
MCE
CAS
330628-04-1

DESCRIPTION [330628-04-1]

Overview

MDLMFCD00797420
Molecular Weight824.90
Molecular FormulaC43H53N8O7P
SMILESCOC1=CC=C(C(C2=CC=CC=C2)(OC[C@@H]3[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@H](N4C(NC(/N=C\N(C)C)=NC5=O)=C5N=C4)O3)C6=CC=C(OC)C=C6)C=C1

For research use only. We do not sell to patients.

Summary

DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer that can be used in the preparation of oligonucleotides


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 121.23 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2123 mL 6.0613 mL 12.1227 mL
5 mM 0.2425 mL 1.2123 mL 2.4245 mL
10 mM 0.1212 mL 0.6061 mL 1.2123 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (3.03 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (3.03 mM); Clear solution

* All of the co-solvents are available by MCE.