[CAS NO. 33390-42-0] Gartanin
PRODUCTS SPECIFICATIONS [33390-42-0]
DESCRIPTION [33390-42-0]
Overview
| MDL | MFCD09264654 |
|---|---|
| Molecular Weight | 396.43 |
| Molecular Formula | C23H24O6 |
| SMILES | O=C1C2=C(OC3=C(O)C=CC(O)=C13)C(C/C=C(C)\C)=C(O)C(C/C=C(C)/C)=C2O |
Summary
In Vitro
Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways
[1]
.
Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 125 mg/mL ( 315.31 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.5225 mL | 12.6126 mL | 25.2251 mL |
| 5 mM | 0.5045 mL | 2.5225 mL | 5.0450 mL |
| 10 mM | 0.2523 mL | 1.2613 mL | 2.5225 mL |
References
- [1] Gao XY, et al. Gartanin Protects Neurons against Glutamate-Induced Cell Death in HT22 Cells: Independence of Nrf-2 but Involvement of HO-1 and AMPK. Neurochem Res. 2016 Sep;41(9):2267-77.
- [2] Kim MO, et al. Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis. Oncol Rep. 2015 Jul;34(1):139-46.
Synonyms