[CAS NO. 334-48-5] Decanoic acid
PRODUCTS SPECIFICATIONS [334-48-5]
DESCRIPTION [334-48-5]
Overview
| MDL | MFCD00004441 |
|---|---|
| Molecular Weight | 172.27 |
| Molecular Formula | C10H20O2 |
| SMILES | CCCCCCCCCC(O)=O |
Summary
Decanoic acid, a component of medium chain triclycerides, is a brain-penetrant and non-competitive inhibitor of AMPA receptor . Decanoic acid has antiseizure effects [1] [2] [3] .
IC50 & Target
|
AMPA Receptor |
Human Endogenous Metabolite |
Appearance
<27°C Solid,>32°C Liquid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Pure form | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 130 mg/mL ( 754.63 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 5.8048 mL | 29.0242 mL | 58.0484 mL |
| 5 mM | 1.1610 mL | 5.8048 mL | 11.6097 mL |
| 10 mM | 0.5805 mL | 2.9024 mL | 5.8048 mL |
References
- [1] Boison D, et, al. New insights into the mechanisms of the ketogenic diet. Curr Opin Neurol. 2017 Apr;30(2):187-192.
- [2] Chang P, et al. Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain. 2016 Feb;139(Pt 2):431-43.
- [3] Kim S, et, al. Selective production of decanoic acid from iterative reversal of β-oxidation pathway. Biotechnol Bioeng. 2018 May;115(5):1311-1320.
Synonyms