[CAS NO. 339-43-5] Carbutamide

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PRODUCTS SPECIFICATIONS [339-43-5]

Catalog

HY-W011651

Brand

MCE

CAS

339-43-5

DESCRIPTION [339-43-5]

Overview

MDL	-
Molecular Weight	271.34
Molecular Formula	C11H17N3O3S
SMILES	O=S(C1=CC=C(N)C=C1)(NC(NCCCC)=O)=O

For research use only. We do not sell to patients.

Summary

Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity ^[1] .

In Vivo

Carbutamide is a sulfonylurea derivative that will cause hypoglycemia when administered by mouth to normal animals ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 184.27 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6854 mL	18.4271 mL	36.8541 mL
5 mM	0.7371 mL	3.6854 mL	7.3708 mL
10 mM	0.3685 mL	1.8427 mL	3.6854 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.17 mg/mL (8.00 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (7.67 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (7.67 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

Benzenesulfonamide, 4-amino-N-[(butylamino)carbonyl]-

Urea, 1-butyl-3-sulfanilyl-

Sulfanilamide, N¹-(butylcarbamoyl)-

4-Amino-N-[(butylamino)carbonyl]benzenesulfonamide

BZ 55

U 6987

Alentin

N-(4-Aminobenzenesulfonyl)-N′-butylurea

Aminophenurobutane

Bucarban

Bucrol

Burcol

N′-(Butylcarbamoyl)sulfanilamide

N-Butyl-N′-sulfanilylurea

1-Butyl-3-sulfanilylurea

Carbutamide

Emedan

Glucidoral

Glybutamide

Invenol

Nadisan

Norboral

Oranil

Orasulin

Diaboral

Oranyl

N′-(4-Aminobenzenesulfonyl)-N-butylurea

N′-(4-Aminophenylsulfonyl)-N-butylurea

N′-(4-Aminophenylsulfonyl)-N-n-butylurea

Carbutamid

N-Sulfanilyl-N′-butylurea

Bukarban

Nadizan

Butisulfina

Inbuton

Glucofren

NSC 242409

NSC 246862

1-(4-Aminophenyl)sulfonyl-3-butylurea