[CAS NO. 34221-41-5] Echinatin

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PRODUCTS SPECIFICATIONS [34221-41-5]

Catalog

HY-N0269

Brand

MCE

CAS

34221-41-5

DESCRIPTION [34221-41-5]

Overview

MDL	MFCD00075719
Molecular Weight	270.28
Molecular Formula	C16H14O4
SMILES	O=C(C1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C=C2OC

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Front Cell Dev Biol. 2021 Jun 11;9:684393.

Summary

Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects ^[1] . Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat ^[2] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 462.48 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6999 mL	18.4993 mL	36.9987 mL
5 mM	0.7400 mL	3.6999 mL	7.3997 mL
10 mM	0.3700 mL	1.8499 mL	3.6999 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.17 mg/mL (8.03 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (7.70 mM); Clear solution

* All of the co-solvents are available by MCE.