[CAS NO. 351490-27-2]  SB-423562

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PRODUCTS SPECIFICATIONS [351490-27-2]

Catalog
HY-15105
Brand
MCE
CAS
351490-27-2

DESCRIPTION [351490-27-2]

Overview

MDLMFCD19443794
Molecular Weight436.54
Molecular FormulaC26H32N2O4
SMILESOC(CCC1=CC=C(C#N)C(OC[C@H](O)CNC(C)(C)CC2CC(C=CC=C3)=C3C2)=C1)=O

For research use only. We do not sell to patients.

Summary

SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 5 mg/mL ( 11.45 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2907 mL 11.4537 mL 22.9074 mL
5 mM 0.4581 mL 2.2907 mL 4.5815 mL
10 mM 0.2291 mL 1.1454 mL 2.2907 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1 mg/mL (2.29 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 1 mg/mL (2.29 mM); Clear solution

* All of the co-solvents are available by MCE.