[CAS NO. 358343-63-2] hMAO-B-IN-5

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PRODUCTS SPECIFICATIONS [358343-63-2]

Catalog

HY-W083062

Brand

MCE

CAS

358343-63-2

DESCRIPTION [358343-63-2]

Overview

MDL	-
Molecular Weight	358.43
Molecular Formula	C24H22O3
SMILES	O=C(C1=CC=C(OCC)C=C1)/C=C/C2=CC=C(OCC3=CC=CC=C3)C=C2

For research use only. We do not sell to patients.

Summary

hMAO-B-IN-5(B15) is a potent, selective and reversible inhibitor of human monoamine oxidase hMAO-B with IC ₅₀ of 0.12 μM. hMAO-B-IN-5 can pass through the blood-brain barrier and can be used in the research of neurodegenerative diseases ^[1] .

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References

[1] Sachithra Thazhathuveedu Sudevan, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12(1):22404.