[CAS NO. 3719-45-7] 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

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PRODUCTS SPECIFICATIONS [3719-45-7]

Catalog

HY-N4226

Brand

MCE

CAS

3719-45-7

DESCRIPTION [3719-45-7]

Overview

MDL	MFCD00031002
Molecular Weight	153.14
Molecular Formula	C7H7NO3
SMILES	O=C(C(C=C1)=CN(C)C1=O)O

For research use only. We do not sell to patients.

Summary

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is from Cordyceps bassiana , which is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function ^[1] .

Appearance

Solid

Source

Cordyceps bassiana

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 653.00 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.5300 mL	32.6499 mL	65.2997 mL
5 mM	1.3060 mL	6.5300 mL	13.0599 mL
10 mM	0.6530 mL	3.2650 mL	6.5300 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (16.32 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (16.32 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (16.32 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Suh W, et al. Chemical Constituents Identified from Fruit Body of and Their Anti-Inflammatory Activity. Biomol Ther (Seoul). 2017 Mar 1;25(2):165-170.