[CAS NO. 3934-84-7] 3-O-Methylgallic acid
PRODUCTS SPECIFICATIONS [3934-84-7]
DESCRIPTION [3934-84-7]
Overview
| MDL | MFCD00016518 |
|---|---|
| Molecular Weight | 184.15 |
| Molecular Formula | C8H8O5 |
| SMILES | O=C(O)C1=CC(OC)=C(O)C(O)=C1 |
Summary
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC 50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects [1] [2] .
Appearance
Solid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 50 mg/mL ( 271.52 mM ; Need ultrasonic)
H 2 O : 2.2 mg/mL ( 11.95 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 5.4304 mL | 27.1518 mL | 54.3036 mL |
| 5 mM | 1.0861 mL | 5.4304 mL | 10.8607 mL |
| 10 mM | 0.5430 mL | 2.7152 mL | 5.4304 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 3.33 mg/mL (18.08 mM); Clear solution; Need ultrasonic
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (13.58 mM); Clear solution
References
- [1] Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7.
- [2] Forester SC, The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. Mol Carcinog. 2014 Jun;53(6):432-9.
Synonyms