[CAS NO. 4233-96-9]  (-)-Gallocatechingallate

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PRODUCTS SPECIFICATIONS [4233-96-9]

Catalog
HY-N0522
Brand
MCE
CAS
4233-96-9

DESCRIPTION [4233-96-9]

Overview

MDLMFCD00214298
Molecular Weight458.37
Molecular FormulaC22H18O11
SMILESO=C(O[C@H]1[C@H](C2=CC(O)=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1)C4=CC(O)=C(O)C(O)=C4

For research use only. We do not sell to patients.


Summary

(-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities.


In Vitro

The amount of (-)-Gallocatechin gallate does not differ in leaves of different stages, and the content is relatively low [1] . (−)-gallocatechin gallate in combination with active catechins ((−)-epigallocatechin gallate) has synergistic effects on the induction of apoptosis and inhibition of cell growth for PC-9 cells. (−)-gallocatechin gallate shows inhibitory effect on α-Glucosidase and DPPH, with IC 50 s of 30.2 μM and 12.2 μg/mL [2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL ( 218.16 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1816 mL 10.9082 mL 21.8164 mL
5 mM 0.4363 mL 2.1816 mL 4.3633 mL
10 mM 0.2182 mL 1.0908 mL 2.1816 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (4.54 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.54 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.54 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester
Gallocatechol, 3-gallate, (-)-
Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2S-trans)-
Gallic acid, ester with gallocatechol, (-)
(-)-Gallocatechin gallate
(-)-Gallocatechol gallate
(-)-Gallocatechin 3-O-gallate
NVP-XAA 225
(-)-Gallocatechin 3-gallate
L-GCG