[CAS NO. 42719-32-4]  Pedunculoside

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PRODUCTS SPECIFICATIONS [42719-32-4]

Catalog
HY-N0458
Brand
MCE
CAS
42719-32-4

DESCRIPTION [42719-32-4]

Overview

MDLMFCD01632712
Molecular Weight650.84
Molecular FormulaC36H58O10
SMILESO[C@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)=O)[C@@]4([H])[C@](C)(O)[C@H](C)CC5)([H])[C@@]1(CO)C

For research use only. We do not sell to patients.

Summary

Pedunculoside exerts lipid-lowering effects partly through the regulation of lipogenesis and fatty acid β-oxidation [1] .


In Vitro

Pedunculoside is a triterpene saponin extracted from Ilex rotunda Thunb. Pedunculoside regulates PPAR-γ, CCAAT/Enhancer-binding Protein α(C/EBPα)、and SREBP-1 expression as well as inhibited phosphorylation of AMPK in MDI (methylisobutylxanthine, dexamethasone, insulin) induced-3T3L1 cells [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 153.65 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5365 mL 7.6824 mL 15.3648 mL
5 mM 0.3073 mL 1.5365 mL 3.0730 mL
10 mM 0.1536 mL 0.7682 mL 1.5365 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (3.84 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (3.84 mM); Clear solution

* All of the co-solvents are available by MCE.