[CAS NO. 432-60-0] Allylestrenol

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PRODUCTS SPECIFICATIONS [432-60-0]

Catalog

HY-17375

Brand

MCE

CAS

432-60-0

DESCRIPTION [432-60-0]

Overview

MDL	-
Molecular Weight	300.48
Molecular Formula	C21H32O
SMILES	C[C@@]12[C@](O)(CC=C)CC[C@@]1([H])[C@]3([H])CCC4=CCCC[C@]4([H])[C@@]3([H])CC2

For research use only. We do not sell to patients.

Summary

Allylestrenol, a synthetic sexualsteroid, is used worldwide in case of endangered pregnancies.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL ( 166.40 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3280 mL	16.6400 mL	33.2801 mL
5 mM	0.6656 mL	3.3280 mL	6.6560 mL
10 mM	0.3328 mL	1.6640 mL	3.3280 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (8.32 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (8.32 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (8.32 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Pap E, et al. Effect of prenatal allylestrenol treatment (hormonal imprinting) on the serum testosterone and progesterone level in adult rats. Gen Pharmacol. 1995 Mar;26(2):365-7.

Synonyms

Estr-4-en-17-ol, 17-(2-propen-1-yl)-, (17β)-

Estr-4-en-17β-ol, 17-allyl-

Estr-4-en-17-ol, 17-(2-propenyl)-, (17β)-

(17β)-17-(2-Propen-1-yl)estr-4-en-17-ol

Allylestrenol

17α-Allylestr-4-en-17β-ol

17α-Allyl-17β-hydroxy-Δ⁴-estren

Gestanin

Gestanon

17α-Allylestrenol

Gestanol

Orageston

Turinal

17α-Allyl-4-oestren-17β-ol

NSC 37723