[CAS NO. 444287-49-4] TNF-α-IN-1

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PRODUCTS SPECIFICATIONS [444287-49-4]

Catalog

HY-112275

Brand

MCE

CAS

444287-49-4

MDL	MFCD29053130
Molecular Weight	363.75
Molecular Formula	C16H14ClN3O5
SMILES	O=C(NCC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCl

For research use only. We do not sell to patients.

TNF-α-IN-1 is a TNF-α inhibitor extracted from patent US20030096841A1, compound example I-7.

TNF-α ^[1]

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 200 mg/mL ( 549.83 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 5 mg/mL (13.75 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 5 mg/mL (13.75 mM); Clear solution

* All of the co-solvents are available by MCE.