[CAS NO. 444932-31-4]  TC-O 9311

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PRODUCTS SPECIFICATIONS [444932-31-4]

Catalog
HY-101777
Brand
MCE
CAS
444932-31-4

DESCRIPTION [444932-31-4]

Overview

MDLMFCD02372953
Molecular Weight365.38
Molecular FormulaC20H19N3O4
SMILESO=C(NNC(NC1=C2C=CC=CC2=CC=C1)=O)C3=CC(OC)=CC(OC)=C3

For research use only. We do not sell to patients.

Summary

TC-O 9311 is a potent orphan G protein-coupled receptor 139 (GPR139) agonist with an EC 50 of 39 nM [1] .


IC50 & Target

EC50: 39 nM (Orphan G protein-coupled receptor 139) [1]


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 342.11 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7369 mL 13.6844 mL 27.3688 mL
5 mM 0.5474 mL 2.7369 mL 5.4738 mL
10 mM 0.2737 mL 1.3684 mL 2.7369 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (5.69 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.69 mM); Clear solution

* All of the co-solvents are available by MCE.