[CAS NO. 4550-72-5]  NSC 15364

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PRODUCTS SPECIFICATIONS [4550-72-5]

Catalog
HY-108937
Brand
MCE
CAS
4550-72-5

DESCRIPTION [4550-72-5]

Overview

MDLMFCD00797928
Molecular Weight242.28
Molecular FormulaC13H14N4O
SMILESO=C(NC1=CC=C(N)C=C1)NC2=CC=C(N)C=C2

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis [1] .


In Vitro

Mitochondrial membrane protein voltage-dependent anion channel 1 (VDAC1) oligomerization represents a prime target for agents designed to modulate apoptosis [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 206.37 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1275 mL 20.6373 mL 41.2746 mL
5 mM 0.8255 mL 4.1275 mL 8.2549 mL
10 mM 0.4127 mL 2.0637 mL 4.1275 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (10.32 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (8.59 mM); Clear solution

* All of the co-solvents are available by MCE.