[CAS NO. 4630-20-0] 3-Methylcarbazole

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PRODUCTS SPECIFICATIONS [4630-20-0]

Catalog

HY-W047478

Brand

MCE

CAS

4630-20-0

DESCRIPTION [4630-20-0]

Overview

MDL	MFCD00464338
Molecular Weight	181.23
Molecular Formula	C13H11N
SMILES	CC1=CC2=C(C=C1)NC3=C2C=CC=C3

For research use only. We do not sell to patients.

Summary

3-Methylcarbazole is an carbazole alkaloid compound with anticancer effects. 3-Methylcarbazole shows growth inhibitory activity (IC ₅₀ of 25 μg/mL) on human fibrosarcoma HT-1080 cells ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 551.79 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.5179 mL	27.5893 mL	55.1785 mL
5 mM	1.1036 mL	5.5179 mL	11.0357 mL
10 mM	0.5518 mL	2.7589 mL	5.5179 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: 2.5 mg/mL (13.79 mM); Suspended solution; Need ultrasonic

* All of the co-solvents are available by MCE.

References

[1] Cheng-Bin Cui, et al. Carbazole alkaloids as new cell cycle inhibitor and apoptosis inducers from Clausena dunniana Levl. J Asian Nat Prod Res. 2002 Dec;4(4):233-41.

Synonyms

9H-Carbazole, 3-methyl-

Carbazole, 3-methyl-

3-Methyl-9H-carbazole

3-Methylcarbazole

6-Methylcarbazole

NSC 10154