[CAS NO. 474-07-7] Brazilin

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PRODUCTS SPECIFICATIONS [474-07-7]

Catalog

HY-N0072

Brand

MCE

CAS

474-07-7

DESCRIPTION [474-07-7]

Overview

MDL	-
Molecular Weight	286.28
Molecular Formula	C16H14O5
SMILES	OC1=CC=C([C@]2([H])[C@](CC3=C2C=C(O)C(O)=C3)(O)CO4)C4=C1

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Summary

Brazilin is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis , and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities ^[1] ^[2] ^[3] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL ( 116.42 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4931 mL	17.4654 mL	34.9308 mL
5 mM	0.6986 mL	3.4931 mL	6.9862 mL
10 mM	0.3493 mL	1.7465 mL	3.4931 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (8.73 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (8.73 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

Benz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol, 7,11b-dihydro-, (6aS,11bR)-

Benz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol, 7,11b-dihydro-, (6aS-cis)-

Brazilin

(6aS,11bR)-7,11b-Dihydrobenz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol

Brasilin

Braziletto

Hypernic Extract

Limawood Extract

Pernambuco Extract

Superbresiline

(+)-Brazilin

NSC 56652

(6AS,11bR)-7,11b-dihydro-6H-indeno[2,1-c]chromene-3,6a,9,10-tetrol