[CAS NO. 480-68-2] 5-Nitrobarbituric acid
PRODUCTS SPECIFICATIONS [480-68-2]
DESCRIPTION [480-68-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 173.08 |
| Molecular Formula | C4H3N3O5 |
| SMILES | O=C1NC(=O)C(C(=O)N1)[N+](=O)[O-] |
Summary
IC50 & Target
|
HSV-1 1.7 μM (IC 50 ) |
In Vitro
5-Nitrobarbituric acid can inhibit vero cell growth [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Cytotoxicity Assay [1]
| Cell Line: | Vero cells |
| Concentration: | 0.06-5 μM |
| Incubation Time: | 2 hours |
| Result: | Showed high cytotoxicity to vero cells. |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 577.77 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 5.7777 mL | 28.8884 mL | 57.7768 mL |
| 5 mM | 1.1555 mL | 5.7777 mL | 11.5554 mL |
| 10 mM | 0.5778 mL | 2.8888 mL | 5.7777 mL |
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: 2.5 mg/mL (14.44 mM); Clear solution; Need ultrasonic
Synonyms