[CAS NO. 4849-90-5] Aristolochic acid C

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PRODUCTS SPECIFICATIONS [4849-90-5]

Catalog

HY-N1450

Brand

MCE

CAS

4849-90-5

DESCRIPTION [4849-90-5]

Overview

MDL	-
Molecular Weight	327.25
Molecular Formula	C16H9NO7
SMILES	O=C(C1=C2C([N+]([O-])=O)=CC3=CC=C(O)C=C3C2=C(OCO4)C4=C1)O

For research use only. We do not sell to patients.

Summary

Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A ₂ ( PLA2 ) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 381.97 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0558 mL	15.2788 mL	30.5577 mL
5 mM	0.6112 mL	3.0558 mL	6.1115 mL
10 mM	0.3056 mL	1.5279 mL	3.0558 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (6.36 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Gardiner J, et al. The phospholipase A inhibitor, aristolochic acid, disrupts cortical microtubule arrays and root growth in . Plant Biol (Stuttg). 2008 Nov;10(6):725-31.