[CAS NO. 492-08-0] (+)-Sparteine
PRODUCTS SPECIFICATIONS [492-08-0]
DESCRIPTION [492-08-0]
Overview
| MDL | MFCD00869353 |
|---|---|
| Molecular Weight | 234.38 |
| Molecular Formula | C15H26N2 |
| SMILES | [H][C@]12CCCCN1C[C@H]3C[C@@H]2CN4CCCC[C@@]34[H] |
Summary
(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.
IC50 & Target
AChR [1]
In Vitro
(+)-Sparteine (2 μM) reduces the ACh-induced current caused by activation of nicotinic AChRs in a voltage-independent manner. (+)-Sparteine (5, 10 μM) reduces the amplitude of the excitatory postsynaptic current (EPSC) and the time constant of the EPSC decay [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Liquid
Source
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H 2 O : 2.86 mg/mL ( 12.20 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.2666 mL | 21.3329 mL | 42.6658 mL |
| 5 mM | 0.8533 mL | 4.2666 mL | 8.5332 mL |
| 10 mM | 0.4267 mL | 2.1333 mL | 4.2666 mL |
Synonyms