[CAS NO. 4929-23-1] BI-0115
PRODUCTS SPECIFICATIONS [4929-23-1]
DESCRIPTION [4929-23-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 287.74 |
| Molecular Formula | C15H14ClN3O |
| SMILES | O=C1N(CCC)C2=CC=CN=C2NC3=CC(Cl)=CC=C13 |
Summary
In Vitro
BI-0115 efficiently reduces oxLDL internalization in the cellular context. The IC 50 values of the cellular assay (5.4 µM) are in good agreement with the determined Kd values in SPR (4.3 µM) and ITC (6.99 µM) [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 347.54 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.4754 mL | 17.3768 mL | 34.7536 mL |
| 5 mM | 0.6951 mL | 3.4754 mL | 6.9507 mL |
| 10 mM | 0.3475 mL | 1.7377 mL | 3.4754 mL |
-
1.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (8.69 mM); Clear solution