[CAS NO. 504-88-1] 3-Nitropropanoic acid
PRODUCTS SPECIFICATIONS [504-88-1]
DESCRIPTION [504-88-1]
Overview
| MDL | MFCD00007406 |
|---|---|
| Molecular Weight | 119.08 |
| Molecular Formula | C3H5NO4 |
| SMILES | O=C(O)CC[N+]([O-])=O |
Summary
IC50 & Target
succinate dehydrogenase [1]
Appearance
Solid
Source
fungi
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 125 mg/mL ( 1049.71 mM ; Need ultrasonic)
H 2 O : 100 mg/mL ( 839.77 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 8.3977 mL | 41.9886 mL | 83.9772 mL |
| 5 mM | 1.6795 mL | 8.3977 mL | 16.7954 mL |
| 10 mM | 0.8398 mL | 4.1989 mL | 8.3977 mL |
References
- [1] Huang LS, et al. 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. J Biol Chem. 2006 Mar 3;281(9):5965-72.
- [2] Chomcheon P, et al. 3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: is 3-NPA in some plants produced by endophytes? J Nat Prod. 2005 Jul;68(7):1103-5.
Synonyms