[CAS NO. 51481-10-8] Deoxynivalenol

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PRODUCTS SPECIFICATIONS [51481-10-8]

Catalog

HY-N6684

Brand

MCE

CAS

51481-10-8

DESCRIPTION [51481-10-8]

Overview

MDL	-
Molecular Weight	296.32
Molecular Formula	C15H20O6
SMILES	O=C(C(C)=C1)[C@@H](O)[C@@]2(CO)[C@]1([H])O[C@]3([H])[C@H](O)C[C@@]2(C)[C@@]34OC4

For research use only. We do not sell to patients.

2 Publications Citing Use of MCE

Summary

Deoxynivalenol, a mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors ^[1] .

Appearance

Solid

Source

Fusarium specie

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

Ethanol : 30 mg/mL ( 101.24 mM ; Need ultrasonic and warming)

DMSO : 25 mg/mL ( 84.37 mM ; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3747 mL	16.8736 mL	33.7473 mL
5 mM	0.6749 mL	3.3747 mL	6.7495 mL
10 mM	0.3375 mL	1.6874 mL	3.3747 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] Sergent T, et al. Deoxynivalenol transport across human intestinal Caco-2 cells and its effects on cellularmetabolism at realistic intestinal concentrations. Toxicol Lett. 2006 Jul 1;164(2):167-76.

Synonyms

Trichothec-9-en-8-one, 12,13-epoxy-3,7,15-trihydroxy-, (3α,7α)-

Spiro[2,5-methano-1-benzoxepin-10,2′-oxirane], trichothec-9-en-8-one deriv.

(3α,7α)-12,13-Epoxy-3,7,15-trihydroxytrichothec-9-en-8-one

Vomitoxin

Dehydronivalenol

Deoxynivalenol

4-Deoxynivalenol

4-Desoxynivalenol

DON

NSC 269144