[CAS NO. 531-58-8] Cichoriin

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PRODUCTS SPECIFICATIONS [531-58-8]

Catalog

HY-N8599

Brand

MCE

CAS

531-58-8

DESCRIPTION [531-58-8]

Overview

MDL	-
Molecular Weight	340.28
Molecular Formula	C15H16O9
SMILES	OC1=C(C=C2C(C=CC(O2)=O)=C1)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO

For research use only. We do not sell to patients.

Summary

Cichoriin is an active compounds against SARS-CoV-2 , and may be a potential candidate in treating severe COVID-19 ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 293.88 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.9388 mL	14.6938 mL	29.3876 mL
5 mM	0.5878 mL	2.9388 mL	5.8775 mL
10 mM	0.2939 mL	1.4694 mL	2.9388 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (7.35 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (7.35 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (7.35 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Rivero-Segura NA, Gomez-Verjan JC. In Silico Screening of Natural Products Isolated from Mexican Herbal Medicines against COVID-19. Biomolecules. 2021;11(2):216. Published 2021 Feb 4.

Synonyms

2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-6-hydroxy-

Cichoriin

7-(β-D-Glucopyranosyloxy)-6-hydroxy-2H-1-benzopyran-2-one

6,7-Dihydroxycoumarin 7-glucoside

Cichorioside

6-Hydroxy-7-(β-D-glucopyranosyloxy)coumarin

Cichorin

6-Hydroxy-7-gluco-coumarin

Cichorin A