[CAS NO. 533-73-3] 1,2,4-Trihydroxybenzene

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PRODUCTS SPECIFICATIONS [533-73-3]

Catalog

HY-W010451

Brand

MCE

CAS

533-73-3

DESCRIPTION [533-73-3]

Overview

MDL	MFCD00002198
Molecular Weight	126.11
Molecular Formula	C6H6O3
SMILES	OC1=CC=C(O)C=C1O

For research use only. We do not sell to patients.

Summary

1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca ²⁺ concentration in rat thymic lymphocytes ^[1] .

Appearance

Solid

Source

Phanerochaete chrysosporium

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 396.48 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.9296 mL	39.6479 mL	79.2959 mL
5 mM	1.5859 mL	7.9296 mL	15.8592 mL
10 mM	0.7930 mL	3.9648 mL	7.9296 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: 2.5 mg/mL (19.82 mM); Suspended solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (19.82 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Risa Kamae, et al. Hydroxyhydroquinone, a by-product of coffee bean roasting, increases intracellular Ca concentration in rat thymic lymphocytes. Food Chem Toxicol. 2017 Apr;102:39-45.

Synonyms

1,2,4-Benzenetriol

Hydroxyhydroquinone

1,2,4-Trihydroxybenzene

2,5-Dihydroxyphenol

1,3,4-Trihydroxybenzene

1,3,4-Benzenetriol

2-Hydroxy-1,4-hydroquinone

2-Hydroxy-p-benzohydroquinone

4-Hydroxycatechol

HHQ

NSC 2818

2-Hydroxyhydroquinone

1,2,5-Benzenetriol