[CAS NO. 553-19-5] Xanthyletin

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PRODUCTS SPECIFICATIONS [553-19-5]

Catalog

HY-N4116

Brand

MCE

CAS

553-19-5

DESCRIPTION [553-19-5]

Overview

MDL	-
Molecular Weight	228.24
Molecular Formula	C14H12O3
SMILES	O=C(O1)C=CC(C1=C2)=CC3=C2OC(C)(C)C=C3

For research use only. We do not sell to patients.

Summary

Xanthyletin is a coumarin isolated from Stauranthus perforatus , with anti-tumor and anti-bacterial activities. Xanthyletin also inhibits symbiotic fungus cultivated by leaf-cutting ants ^[1] .

IC50 & Target

Fugal ^[1] ^[2]

In Vitro

Xanthyletin inhibits symbiotic fungus cultivated by leaf-cutting ants ^[1] .
Xanthyletin (25, 50, and 100 µg/mL) shows a total inhibition on the fungus ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 109.53 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.3814 mL	21.9068 mL	43.8135 mL
5 mM	0.8763 mL	4.3814 mL	8.7627 mL
10 mM	0.4381 mL	2.1907 mL	4.3814 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 1.25 mg/mL (5.48 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 1.25 mg/mL (5.48 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

2H,8H-Benzo[1,2-b:5,4-b′]dipyran-2-one, 8,8-dimethyl-

Xanthyletin

2H-1-Benzopyran-6-acrylic acid, 7-hydroxy-2,2-dimethyl-, δ-lactone

8,8-Dimethyl-2H,8H-benzo[1,2-b:5,4-b′]dipyran-2-one

7-Hydroxy-2,2-dimethyl-2H-1-benzopyran-6-acrylic acid δ-lactone

2,2-Dimethylchromenocoumarin

2,2-Dimethylpyrano[3,2-g]chromen-8-one