[CAS NO. 580-22-3] 2-Aminoquinoline
PRODUCTS SPECIFICATIONS [580-22-3]
DESCRIPTION [580-22-3]
Overview
| MDL | MFCD00038079 |
|---|---|
| Molecular Weight | 144.17 |
| Molecular Formula | C9H8N2 |
| SMILES | NC1=NC2=CC=CC=C2C=C1 |
Summary
2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS , and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents [1] [2] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL ( 693.63 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 6.9363 mL | 34.6813 mL | 69.3626 mL |
| 5 mM | 1.3873 mL | 6.9363 mL | 13.8725 mL |
| 10 mM | 0.6936 mL | 3.4681 mL | 6.9363 mL |
References
- [1] Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60(16):7146-7165.
- [2] Smee DF, et, al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.
Synonyms