[CAS NO. 582-24-1] 2-Hydroxyacetophenone

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PRODUCTS SPECIFICATIONS [582-24-1]

Catalog

HY-W002198

Brand

MCE

CAS

582-24-1

DESCRIPTION [582-24-1]

Overview

MDL	MFCD00041829
Molecular Weight	136.15
Molecular Formula	C8H8O2
SMILES	O=C(C1=CC=CC=C1)CO

For research use only. We do not sell to patients.

Summary

2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis ^[1] . 2-Hydroxyacetophenone shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC ₅₀ of 1.8 mM ^[2] .

IC50 & Target

HIV

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 12.5 mg/mL ( 91.81 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.3448 mL	36.7242 mL	73.4484 mL
5 mM	1.4690 mL	7.3448 mL	14.6897 mL
10 mM	0.7345 mL	3.6724 mL	7.3448 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (18.36 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

Ethanone, 2-hydroxy-1-phenyl-

Acetophenone, 2-hydroxy-

Acetophenone, α-hydroxy-

2-Hydroxy-1-phenylethanone

Benzoylcarbinol

Glycolophenone

Methanol, benzoyl-

Phenacyl alcohol

2-Hydroxyacetophenone

α-Hydroxyacetophenone

ω-Hydroxyacetophenone

(Hydroxyacetyl)benzene

Benzoylmethanol

2-Phenyl-2-oxoethanol

NSC 171232

Hydroxymethyl phenyl ketone

1-Phenyl-2-hydroxyethanone

2-Hydroxy-1-phenylethan-1-one