[CAS NO. 59-06-3] Ethopabate

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PRODUCTS SPECIFICATIONS [59-06-3]

Catalog

HY-B2138

Brand

MCE

CAS

59-06-3

DESCRIPTION [59-06-3]

Overview

MDL	MFCD00075809
Molecular Weight	237.25
Molecular Formula	C12H15NO4
SMILES	O=C(OC)C1=CC=C(NC(C)=O)C=C1OCC

For research use only. We do not sell to patients.

Summary

Ethopabate is an antiprotozoal agent which has been widely used to treat and prevent coccidiosis in chickens.

IC50 & Target

Coccidia

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 210.75 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.2150 mL	21.0748 mL	42.1496 mL
5 mM	0.8430 mL	4.2150 mL	8.4299 mL
10 mM	0.4215 mL	2.1075 mL	4.2150 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (10.54 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (10.54 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (10.54 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Hussein LA, et al. Five different spectrophotometric methods for determination of Amprolium hydrochloride and Ethopabate binary mixture. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Mar 5;138:395-405.

Synonyms

Benzoic acid, 4-(acetylamino)-2-ethoxy-, methyl ester

Benzoic acid, 4-acetamido-2-ethoxy-, methyl ester

Ethopabate

Methyl 4-acetamido-2-ethoxybenzoate

4-Acetamido-2-ethoxybenzoic acid methyl ester

Ethyl pabate

Methyl 4-(acetylamino)-2-ethoxybenzoate

Methyl 2-ethoxy-4-acetamidobenzoate